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  • 药用丁基胶塞与注射用阿莫西林钠的相容性研究

    目的 考察药用丁基胶塞与注射用阿莫西林钠的相容性情况.方法 通过平行加速试验,考察使用丁基胶塞前后的注射用阿莫西林钠溶液的颜色与澄清度、有关物质、高聚物.结果 7个生产厂家的丁基胶塞均对注射用阿莫西林钠的稳定性无影响.结论 目前国产注射用阿莫西林钠所使用的药用丁基胶塞总体情况良好且与药品活性成分相容性良好.
    殷果,秦斌,王铁杰,邓颖,李军,周劼 - 中国抗生素杂志
    文章来源: 万方数据
  • The current development of precision plastic injection molding machines mainly focuses on how to save material and improve precision, but the two aims contradict each other. For a clamp unit, clamping precision improving depends on the design quality of the stationary platen. Compared with the parametric design of stationary platen, structural scheme design could obtain the optimization model with double objectives and multi-constraints. In this paper, a SE-160 precision plastic injection molding machine with 1600 kN clamping force is selected as the subject in the case study. During the motion of mold closing and opening, the stationary platen of SE-160 is subjected to a cyclic loading, which would cause the fatigue rupture of the tie bars in periodically long term operations. In order to reduce the deflection of the stationary platen, the FEA method is introduced to optimize the structure of the stationary platen. Firstly, an optimal topology model is established by variable density method. Then, structural topology optimizations of the stationary platen are done with the removable material from 50%, 60% to 70%. Secondly, the other two recommended optimization schemes are given and compared with the original structure. The result of performances comparison shows that the scheme II of the platen is the best one. By choosing the best alternative, the volume and the local maximal stress of the platen could be decreased, corresponding to cost-saving material and better mechanical properties. This paper proposes a structural optimization design scheme, which can save the material as well as improve the clamping precision of the precision plastic injection molding machine.
     - 中国机械工程学报
    文章来源: 万方数据
  • 油封成型工艺分析与注射模设计

    采用PFA材料所成型的油封在机床油管中起到密封和显示油液位置的作用,以解决机床油路部分漏油的问题.为确保油封质量合格,运用CAE软件Moldflow模拟了油封塑料熔体在模具模腔中的流动、保压、冷却过程,预测制品可能发生的翘曲、气穴、熔接痕等缺陷,据此对油封模具的结构和注塑工艺参数优化,并介绍外骨架油封批量生产的模具设计及工作过程,提高了一次试模的成功率,加快了模具开发进度,进而缩短产品开发周期,提高企业的配套能力和产品质量.
    董海东 - 塑料
    文章来源: 万方数据
  • 电热水壶底座浇口方案CAE分析及验证

    利用Moldflow的AMI 2011 Performance模块,对热水壶底座注塑模的2种浇口方案进行了模拟分析.分析比较了2种进胶方案的流动平衡,注射压力,翘曲变形等方面,并通过实际注塑结果进行验证.
    李峰,李永泉,孙晋 - 塑料
    文章来源: 万方数据
  • CAE技术在注塑模冷却水道优化设计中的应用

    注塑模设计过程中,冷却水道布局的好坏,关系到塑件的成型质量和成型周期.以某深腔塑件为例,阐述了CAE技术在注塑模冷却水道优化设计中的应用方法和意义.
    董金虎 - 塑料
    文章来源: 万方数据
  • 玫瑰茄提取物对Wistar大鼠肾Na+-K+-ATP酶及Ca2+-Mg2+-ATP酶活性的影响

    目的:研究口服玫瑰茄水提取物对大鼠肾Na+-K+-ATP酶和Ca2+- Mg2+-ATP酶活性的影响.方法:连续28 d分别给予实验大鼠口服25和50 mg/kg的玫瑰茄水提物,同时给予对照组大鼠灌胃适当剂量的蒸馏水.用光谱测定法分析大鼠肾脏中Na+-K+-ATP酶和Ca2+ -Mg2+-ATP酶的活性.结果:口服25和50 mg/kg的玫瑰茄提取物后,实验组大鼠肾Ca2+-Mg2+-ATP酶活性显著降低(P<0.05),然而肾Na+ -K+ -ATP酶的活性却未受到任何影响.实验组大鼠体质量、肾脏质量,血浆白蛋白和总蛋白浓度,碱性磷酸酶、天冬氨酸氨基转移酶、丙氨酸氨基转移酶活性以及血浆钠、钾、钙离子的浓度与对照组大鼠相比无明显变化;但大鼠的肌酐以及尿素水平均在服用50 mg/kg的玫瑰茄提取物后明显降低(P<0.05).结论:尽管口服玫瑰茄提取物会引起肾Ca2+-Mg2+-ATP酶活性的减弱,但同时可以起到保护肾脏功能的作用.
    Lawrence A. Olatunji, Taofeek O. Usman, Joseph O. Adebayo, Victoria A. Olatunji - 中西医结合学报
    文章来源: 万方数据
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