科创中国

目的 观察养精胶囊对老年雄性SD大鼠性功能的影响,并探讨其可能的影响机制.方法 将40只老年雄性SD大鼠随机分为实验组和对照组,实验组给予养精胶囊(0.5g/kg·d-1)灌胃4周,对照组给予等剂量生理盐水灌胃相同时间.4周后通过观察两组大鼠阴茎勃起变化、检测血清睾酮水平和免疫组化方法检测大鼠阴茎海绵体组织中内皮型一氧化氮合酶(eNOS)及海绵体组织血管中CD34分子表达的变化情况等评价大鼠性功能变化情况.结果 (1)对照组老年大鼠干预后血清总睾酮水平较干预前下降,但组间比较差异无统计学意义(P>0.05);养精胶囊组老年大鼠干预后血清总睾酮水平较干预前有所提高,但差异亦无统计学意义(P>0.05);(2)在老年大鼠性功能指标方面:养精胶囊干预组老年大鼠阴茎勃起次数、勃起潜伏期及勃起维持时间均较对照组有所改善.(3)阴茎海绵体组织HE染色结果提示:养精胶囊组老年大鼠阴茎海绵体组织血管管腔明显扩张,充血,管腔内壁变薄;对照组老年大鼠阴茎海绵体组织内,血管管腔未见明显充盈扩张,管腔内充血不明显,且管腔有大量残留的陈旧性血液.(4)免疫组化结果提示:两组大鼠海绵体组织中,均可见深染的棕褐色阳性颗粒,但深染程度和颗粒分布密度不一.低倍镜(*100)视野下观察,药物干预后实验组大鼠阴茎海绵体组织中eNOS的阳性颗粒的数量明显高于对照组(P<0.05);(5)微血管密度结果提示:实验组老年大鼠阴茎海绵体组织血管内皮中CD34的表达明显强于对照组,高倍镜下(*400)观察,实验组微血管密度MVD值较对照组升高(P<0.05).结论 养精胶囊能促进血清睾酮的分泌,增强阴茎海绵体组织内eNOS的表达,这可能是养精胶囊改善大鼠性功能和阴茎勃起的作用机制.

Layered organic-inorganic hybrids containing bilayer perovsikte (R-NH3)2(CH3NH3)Pb2I7 (where R=C12H25,C6H5C2H4) were synthesized by reactions in solution. The influences of the solvents and the reactant ratio on the structures of the products were investigated. The structures and the properties of the hybrids were characterized using X-ray diffraction (XRD) and ultraviolet and visible (UV) adsorption spectra. For comparing with the bilayer perovskite hybrids in structure and band gap magnitude, the hybrids containing monolayer perovskite (R-NH3)2PbI4 were also synthesized and characterized. The results demonstrate that the thickness of inorganic layer has obvious effect on the tunneling magnitude of the band gap but the organic part can be micro actuator of band gap.

Dual mechanical port machine(DMPM), as a novel electromechanical energy conversion device, has attracted widespread attention. DMPM with spoke type permanent magnet arrangements(STPM-DMPM), which is one of several types of DMPM, has been of interest recently. The unique coupling characteristics of STPM-DMPM are beneficial to improving system performance, but these same characteristics increase the difficulties of control. Now there has been little research about the control of STPM-DMPM, and this has hindered its practical application. Based on a mathematical model of STPM-DMPM, the coupling characteristics and the merits and demerits of such devices are analyzed as applied to a hybrid system. The control strategies for improving the disadvantages and for utilizing the advantage of coupling are researched. In order to weaken the interaction effect of torque outputs in the inner motor and the outer motor that results from coupling in STPM-DMPM, a decoupling control method based on equivalent current control is proposed, and independent torque control for the inner motor and outer motor is achieved. In order to solve address the problem of adequately utilization of coupling, minimizing the overall copper loss of the inner motor and the outer motor of STPM-DMPM is taken as the optimization objective for optimal control, and the purpose of utilizing the coupling adequately and reasonably is achieved. The verification tests of the proposed decoupling control and optimal control strategies are carried out on a prototype STPM-DMPM, and the experimental results show that the interaction effect of torque outputs in the inner motor and the outer motor can be markedly weakened through use of the control method. The overall copper loss of the inner motor and the outer motor can be markedly reduced through use of the optimal control method, while the power output remains unchanged. A breakthrough in the control problem of STPM-DMPM is accomplished by combining the control methods. Good performance in the control of STPM-DMPM will enhance its practicality, particularly as applied to hybrid systems.

The identification of maximum road friction coefficient and optimal slip ratio is crucial to vehicle dynamics and control.However,it is always not easy to identify the maximum road friction coefficient with high robustness and good adaptability to various vehicle operating conditions.The existing investigations on robust identification of maximum road friction coefficient are unsatisfactory.In this paper,an identification approach based on road type recognition is proposed for the robust identification of maximum road friction coefficient and optimal slip ratio.The instantaneous road friction coefficient is estimated through the recursive least square with a forgetting factor method based on the single wheel model,and the estimated road friction coefficient and slip ratio are grouped in a set of samples in a small time interval before the current time,which are updated with time progressing.The current road type is recognized by comparing the samples of the estimated road friction coefficient with the standard road friction coefficient of each typical road,and the minimum statistical error is used as the recognition principle to improve identification robustness.Once the road type is recognized,the maximum road friction coefficient and optimal slip ratio are determined.The numerical simulation tests are conducted on two typical road friction conditions(single-friction and joint-friction)by using CarSim software.The test results show that there is little identification error between the identified maximum road friction coefficient and the pre-set value in CarSim.The proposed identification method has good robustness performance to external disturbances and good adaptability to various vehicle operating conditions and road variations,and the identification results can be used for the adjustment of vehicle active safety control strategies.

粒子谱演变过程的数值模拟应用于粉体材料的制备过程,对于认识粒子的生成规律、优化生产条件、辅助设计制备设备具有一定的帮助作用.本文在分析制备过程特点的基础上,建立了粒子形成过程的控制方程,并利用Fluent软件对流体流动的控制方程、粒子谱演变方程及粒子的体积浓度方程构成的方程组进行了求解.模拟结果表明,氧化铋粒子的成核与凝并过程都发生在很短的时间内,较小的空间范围内,因此,所得粒子的大小受流体下游冷却系统的影响较小.在这个制备系统中,氧化铋粒子的数值浓度较低,易生成粒度较小的粒子.在反应舟区流体的径向速度较大,在炉子出口处,热迁移速度较大,氧化铋有可能在这2个地方向反应器壁沉积,造成产品产率降低.数值模拟不同制备温度下氧化铋粒度大小与实验结果基本一致.

通过模拟水管式沉降仪埋设安装条件,按照监测规范及相关技术要求,结合水管式沉降仪测值计算及修正原理,对糯扎渡水电站水管式沉降仪模拟实验场地布置、材料要求、安装及坝料回填过程进行实验.监测数据结果表明,实验测点最大沉降分别为145 mm和37 mm,水管式沉降仪器整体测值稳定,波动变化较小,对于在糯扎渡高土石坝具有良好的适用性.

首先给出了若干标量Young型不等式.然后在此基础上,建立了相应的矩阵Young型不等式.

根据衡水市浅层地下水的水质监测资料,采用地下水环境质量标准,污染物主要有溶解性总固体、氨氮、锰、总硬度、硫酸盐、氟化物、高锰酸盐指数、氯化物等.综合污染指数总体呈下降趋势;并对硫酸盐、高锰酸盐指数、氨氮、锰主要污染物质进行变化趋势,受外界影响,其变化幅度较大.最后提出地下水保护措施和建议,为衡水市地下水资源合理开发利用提供参考依据.

经平绒是一种高档面料,在使用过程中易出现绒毛倒伏的现象,影响服饰美观.综合了针织"不倒绒"和机织长毛绒织物的特点,提出了用机织技术生产"不倒绒"经平绒机织面料的方法,阐述了原料选择、组织设计、固结方式选择、绒毛高度确定以及上机工艺参数设置等关键技术.研制的经平绒面料绒毛耸立,不易变形;面料光泽柔和,手感滑糯,弹性良好.

为进一步了解衡水市地表水质的时空变化规律,现从地表水化学特征、河流湖库现状水质、水质变化趋势等方面分析和评价了衡水市地表水资源质量状况,并对加强当地水资源保护工作,提出了措施与建议.衡水湖是国家级湿地自然保护区,对衡水市的持续发展有极其重要的作用,对此,本文重点对衡水湖的水质状况、综合污染情况等进行了分析研究.