科创中国

Interferon-β-armed oncolytic adenovirus induces both apoptosis and necroptosis in cancer cells

原文链接：万方

• 作者：

  Hongling Huang, Tian Xiao, Lingfeng He, Hongbin Ji, Xin-Yuan Liu

• 关键词：

  细胞凋亡 肿瘤细胞 干扰素 腺病毒 坏死 caspase IFN-α 诱导 IFN-β cell cycle arrest apoptosis necroptosis synergism

• 作者单位：

  State Key Laboratory of Cell Biology, Institute of Biochemistry and Cell Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China%Xinyuan Institute of Medicine and Biotechnology, Zhejiang Sci-Tech University, Hangzhou 310018, China%Department of Medicine, Beth Israel and Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA

• 基金项目：

  This work was supported by the grants from the National Natural Science Foundation of China （30623003 and 81172449）; National Basic Research Program of China （973 Program） （2010CB529901 and 2011CB510104）;Important National Science ＆ Technology Specific Project of Hepatitis and Hepatoma Related Program （2008ZX10002- 023）; New Innovation Program （2009-ZX-09102-246）;and Zhejiang Sci-Tech University grant （1016834-Y）.

• DOI：

  10.1093/abbs/gms060

• 来源期刊：

  生物化学与生物物理学报(英文版)

• 年，卷(期)：

  201244009