科创中国

《东方之旅》是黑塞最重要的作品之一.它蕴含了作者大半生的对人的内在精神世界以及人类文化所作的思考和总结.黑塞将中国老子哲学思想与西方宗教文化融于作品之中,运用比喻、暗喻等手法表述深刻的思想内涵,使人物和情节都给人以神秘、魔幻的感觉.主人公雷欧兼具东西方文化的特征,这种多文化互补的形式才是人类心灵的寓所."双体人像"的情节则暗示了人类各民族文化是一个整体,与自然、宇宙和谐共生.《东方之旅》展现了黑塞的多文化和谐共存思想.

The classical natural coordinate modeling method which removes the Euler angles and Euler parameters from the governing equations is particularly suitable for the sensitivity analysis and optimization of multibody systems. However, the formulation has so many principles in choosing the generalized coordinates that it hinders the implementation of modeling automation. A first order direct sensitivity analysis approach to multibody systems formulated with novel natural coordinates is presented. Firstly, a new selection method for natural coordinate is developed. The method introduces 12 coordinates to describe the position and orientation of a spatial object. On the basis of the proposed natural coordinates, rigid constraint conditions, the basic constraint elements as well as the initial conditions for the governing equations are derived. Considering the characteristics of the governing equations, the newly proposed generalized-α integration method is used and the corresponding algorithm flowchart is discussed. The objective function, the detailed analysis process of first order direct sensitivity analysis and related solving strategy are provided based on the previous modeling system. Finally, in order to verify the validity and accuracy of the method presented, the sensitivity analysis of a planar spinner-slider mechanism and a spatial crank-slider mechanism are conducted. The test results agree well with that of the finite difference method, and the maximum absolute deviation of the results is less than 3%. The proposed approach is not only convenient for automatic modeling, but also helpful for the reduction of the complexity of sensitivity analysis, which provides a practical and effective way to obtain sensitivity for the optimization problems of multibody systems.

从国内来看,近年来和谐哲学的研究主流是围绕斗争哲学而展开的,此外,还有一部分学者从系统论和理念创新的角度研究和谐哲学,可视为和谐哲学研究的两条支流.当今和谐哲学命题自身面临着生存危机;和谐哲学的儒化思想严重;和谐哲学理论体系亟待建立等诸多问题.未来的和谐哲学研究内容应扩大眼界,汲取百家之长;和谐哲学研究界域应控制在学术领域,避免将学术争辩上升到政治斗争;和谐哲学研究范围不应仅限于国内,还应扩展到国外.

针对当前基于自然特征的增强现实效率低,提出一种新的基于ORB自然特征的实时注册方法.提取视频帧与基准图像中的ORB特征点,使用汉明距离匹配,利用RANSAC算法筛选得到最佳匹配点对,确定摄像机的位姿.将三维虚拟物体叠加到真实场景中,达到虚实结合的效果.实验表明,在不同尺度角度、一定环境光变化、复杂背景和基准图像部分遮挡的情况下,该AR系统都具有良好的性能,跟踪定位准确度高,速度基本达到实时要求

为了降低药物开发后期的失败率,指导侯筛化合物库的设计,药物化学家提出了许多基于化学信息学或计算化学的"成药性"理论指标,这些预测方法日益成熟,取得了广泛应用.本文综述了现有的化合物成药性预测方法的研究进展,包括类药性、类先导性、类天然产物、类代谢物以及生物相关性等,对比了各种成药性预测方法的特征,分析了各种预测方法的优点及其在组合化合物库的设计和优化中的作用,指出了这些方法的不足和局限性.最后,对化合物的成药性预测的应用前景和发展趋势进行了展望.

《周易》有"大道之原"的美称,虽非诠释造物之道,却包含"造物之道".楚国制器工艺是对《周易》哲学思想的具体阐释和应用,是《周易》"道器说"的组成部分,它们分别从理论和实践两个方面衍生、规范了传统制器工艺文化的基本范畴和美学思想.发掘《周易》与楚国制器工艺的内在联系,对于继承和发展中华独具特色的"道器"文脉体系,具有十分重要的理论价值和现实指导意义.